I’m wondering if anyone has ever used 23andme for genetic testing. I was diagnosed with Celiac through several blood tests and a biopsy 18 years ago. My mother had a positive result for celiac through a blood test and a negative biopsy test, approximately 5 years ago. I know 23andme has limitations and is not always accurate, but there were no variants for Celiac Disease detected on the DNA they tested (HLA-DQA1 and HLA-DQB1). From the research I completed, it seems that the scientific community is claiming that in order to develop this disease you must have either one or both genes. Some of the research indicates that there could be other medical reasons for a positive test (e.g. Crohn’s disease, bacterial infections) but I have also been tested for other digestive disorders over the years with negative results.
I obviously plan on sticking to a gluten free diet based on my medical diagnosis, but I was just surprised to see this result and wondering if anyone has experienced anything similar. Or if anyone has any further research related to the topic that might help me determine next steps. Thanks.